*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TP8800000
CHEMICAL NAME           : Podophyllic acid, 2-ethylhydrazide
CAS REGISTRY NUMBER     : 1508-45-8
LAST UPDATED            : 199012
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C24-H30-N2-O8
MOLECULAR WEIGHT        : 474.56
WISWESSER LINE NOTATION : T C566 DO FO EH&&TJ JQ K1Q LVMM2 MR CO1 DO1 EO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Mitopodozide
   * NSC-72274
   * Podophyllic acid ethylhydrazide
   * Podophyllinic acid 2-ethylhydrazide
   * Proresid
   * Proreside
   * Proresipar
   * SP-I 77
   * SP-I (Pharmaceutical)
   * SP-I Sandoz
   * SP-I
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 140 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 20,1467,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 140 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 20,363,1970
 
                            *** END OF RECORD ***