*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TR7875000
CHEMICAL NAME           : Polyurethane foam
CAS REGISTRY NUMBER     : 9009-54-5
LAST UPDATED            : 199510
DATA ITEMS CITED        : 9
COMPOUND DESCRIPTOR     : Tumorigen
                          Human
SYNONYMS/TRADE NAMES :
   * Andur
   * Curene
   * Etheron
   * Etheron sponge
   * Isourethane
   * NCI-C56451
   * Pliogrip
   * Polyfoam plastic sponge
   * Polyfoam sponge
   * Polyurethane A
   * Polyurethane ester foam
   * Polyurethane ether foam
   * Polyurethane sponge
   * Spenkel
   * Spenlite
   * Urethane polymers
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human
DOSE/DURATION           : 12 mg/m3/11W-C
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - visual field changes
REFERENCE :
   IAEHDW International Archives of Occupational and Environmental Health.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   07094)  V.35-    1975-  Volume(issue)/page/year: 57,297,1986
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intratracheal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 225 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - emphysema
   Lungs, Thorax, or Respiration - fibrosis (interstitial)
REFERENCE :
   EVHPAZ EHP, Environmental Health Perspectives.  (U.S. Government Printing
   Office, Supt of Documents, Washington, DC 20402)  No.1-    1972-
   Volume(issue)/page/year: 11,109,1975
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 293 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   33,1005,1964
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10 gm/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Immunological Including Allergic - increase in cellular immune response
REFERENCE :
   BJSUAM British Journal of Surgery.  (Quadrant Subscription Services Ltd.,
   Oakfield House, Perrymount Rd., Haywards Heath, W. Sussex RH16 3DH, UK) V.1-
      1913-  Volume(issue)/page/year: 52,49,1965

                              *** REVIEWS ***
 
   IARC Cancer Review:Human No Adequate Data
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 19,303,1979

   IARC Cancer Review:Animal Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 19,303,1979

   IARC Cancer Review:Group 3
   IMSUDL IARC Monographs, Supplement.  (WHO Publications Centre USA, 49
   Sheridan Ave., Albany, NY 12210)  No.1-    1979-  Volume(issue)/page/year:
   7,56,1987

   TOXICOLOGY REVIEW
   AOHYA3 Annals of Occupational Hygiene.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958- Volume(issue)/page/year:
   17,143,1974

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X3289
       No. of Facilities: 924 (estimated)
       No. of Industries: 9
       No. of Occupations: 17
       No. of Employees: 22176 (estimated)
       No. of Female Employees: 15667 (estimated)

 
                            *** END OF RECORD ***