*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : TR8370000
CHEMICAL NAME : Poly(1-vinyl-2-pyrrolidinone) homopolymer
CAS REGISTRY NUMBER : 9003-39-8
LAST UPDATED : 199710
DATA ITEMS CITED : 21
MOLECULAR FORMULA : (C6-H9-N-O)x
WISWESSER LINE NOTATION : /T5NVTJ AY*1*/
COMPOUND DESCRIPTOR : Tumorigen
SYNONYMS/TRADE NAMES :
* Agent AT 717
* Agrimer
* Albigen A
* Aldacol Q
* AT 717
* Bolinan
* 1-Ethenyl-2-pyrrolidinone polymers
* Ganex P 804
* Hemodesis
* Hemodez
* K15
* K25
* K25 (polymer)
* K30
* K30 (polymer)
* K60
* K60 (polymer)
* K90
* K115
* K115 (polyamide)
* Kollidon
* Kollidon 17
* Kollidon 25
* Kollidon 30
* Luviskol
* Luviskol K30
* Luviskol K90
* MPK 90
* NCI C60582
* Neocompensan
* Peragal ST
* Peregal ST
* Periston
* Periston-N
* Peviston
* Plasdone
* Plasdone K-26/28
* Plasdone K 29-32
* Plasdone XL
* Plasmosan
* Polyclar AT
* Polyclar H
* Polyclar L
* Poly(1-(2-oxo-1-pyrrolidinyl)ethylene)
* Polyvidone
* Poly(n-vinylbutyrolactam)
* Poly(vinylpyrrolidinone)
* Poly(N-vinylpyrrolidinone)
* Poly(1-vinylpyrrolidinone)
* Polyvinylpyrrolidone
* Povidone
* Povidone (usp xix)
* Protagent
* PVP
* PVP 40
* PVP-K 15
* PVP-K 30
* PVP-K 60
* PVP-K 90
* PVPP
* 2-Pyrrolidinone, 1-ethenyl, homopolymer
* 2-Pyrrolidinone, 1-vinyl-, polymers
* 143 RP
* Subtosan
* Vinisil
* N-Vinylbutyrolactam polymer
* Vinylpyrrolidinone polymer
* N-Vinylpyrrolidinone polymer
* N-Vinylpyrrolidone polymer
* Vinylpyrrolidone polymer
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 100 gm/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57,
1948-77. Discontinued. Volume(issue)/page/year: 53A,486,1974
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >40 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57,
1948-77. Discontinued. Volume(issue)/page/year: 40,164,1967
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 12 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57,
1948-77. Discontinued. Volume(issue)/page/year: 53A,486,1974
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 16 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal.
For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095
Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 19,212,1985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1040 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 61(12),68,1985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 100 gm/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57,
1948-77. Discontinued. Volume(issue)/page/year: 53A,486,1974
*** REVIEWS ***
IARC Cancer Review:Animal Limited Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 19,461,1979
IARC Cancer Review:Human No Adequate Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 19,461,1979
IARC Cancer Review:Group 3
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,56,1987
TOXICOLOGY REVIEW
JJOMDZ JOM, Journal of Occupational Medicine. (American Occupational
Medicine Assoc., 150 N. Wacker Dr., Chicago, IL 60606) V.10- 1968-
Volume(issue)/page/year: 15,808,1973
TOXICOLOGY REVIEW
JSCCA5 Journal of the Society of Cosmetic Chemists. (Soc. of Cosmetic
Chemists, 1995 Broadway, Suite 1701, New York, NY 10023) V.1- 1947-
Volume(issue)/page/year: 5,129,1954
TOXICOLOGY REVIEW
15SWA8 "Kirk-Othmer Encyclopedia of Chemical Technology, 1963-70," 2nd ed.,
Standen, A., et al., eds., New York, John Wiley & Sons, Inc., 1971
Volume(issue)/page/year: 21,427,1970
TOXICOLOGY REVIEW
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57,
1948-77. Discontinued. Volume(issue)/page/year: 53A,486,1974
TOXICOLOGY REVIEW
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 21,1468,1971
TOXICOLOGY REVIEW
PSTGAW Proceedings of the Scientific Section of the Toilet Goods
Association. (Washington, DC) No.1-48, 1944-67. Discontinued.
Volume(issue)/page/year: 38,1,1962
TOXICOLOGY REVIEW
PSTGAW Proceedings of the Scientific Section of the Toilet Goods
Association. (Washington, DC) No.1-48, 1944-67. Discontinued.
Volume(issue)/page/year: 38,1,1962
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 81235
No. of Facilities: 7856 (estimated)
No. of Industries: 50
No. of Occupations: 63
No. of Employees: 102100 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X7211
No. of Facilities: 7688 (estimated)
No. of Industries: 46
No. of Occupations: 63
No. of Employees: 161259 (estimated)
No. of Female Employees: 84819 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***