*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TU3832000
CHEMICAL NAME           : Pregna-1,4-diene-3,20-dione,
                          6-alpha,9-difluoro-11-beta,17,21-trihydroxy-16-alpha-
                          methyl-
CAS REGISTRY NUMBER     : 2135-17-3
BEILSTEIN REFERENCE NO. : 5645455
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C22-H28-F2-O5
MOLECULAR WEIGHT        : 410.50
WISWESSER LINE NOTATION : L E5 B666 OV AHTTT&J A1 BF CQ E1 FV1 FQ G1 LF
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * Anaprime
   * Aniprime
   * Cortexilar
   * Flucort
   * Flucorticin
   * Flumethason
   * Flumethasone
   * 6-alpha-Fluorodexamethasone
   * Fluvet
   * Methagon
   * RS-2177
   * U-10974
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Mammal - cattle
DOSE                    : 20 ug/kg
SEX/DURATION            : female 38 week(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - parturition
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 28,407,1972
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Mammal - cattle
DOSE                    : 30 ug/kg
SEX/DURATION            : female 31 week(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
REFERENCE :
   JAVMA4 Journal of the American Veterinary Medical Association.  (American
   Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196)  V.48-
   1915-  Volume(issue)/page/year: 160,867,1972
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Mammal - cattle
DOSE                    : 20 ug/kg
SEX/DURATION            : female 40 week(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - parturition
REFERENCE :
   THGNBO Theriogenology.  (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022)
   V.1-    1974-  Volume(issue)/page/year: 20,267,1983
 
                            *** END OF RECORD ***