*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TU5011500 CHEMICAL NAME : Pregn-4-ene-3,20-dione, 17,21-dihydroxy- CAS REGISTRY NUMBER : 152-58-9 BEILSTEIN REFERENCE NO. : 2511358 REFERENCE : 4-08-00-02913 (Beilstein Handbook Reference) LAST UPDATED : 199703 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C21-H30-O4 MOLECULAR WEIGHT : 346.51 WISWESSER LINE NOTATION : L E5 B666 OV MUTJ A1 E1 FV1Q FQ COMPOUND DESCRIPTOR : Mutagen SYNONYMS/TRADE NAMES : * Cortexolone * Cortisol, 11-dioxy- * Cortodoxone * 11-Deoxyhydrocortisone * 11-Deoxy-17-hydroxycorticosterone * 11-Desoxycortisol * 11-Desoxyhydrocortisone * 11-Desoxy-17-hydroxycorticosterone * 17,21-Dihydroxy-4-pregnene-3,20-dione * 17,21-Dihydroxyprogesterone * 11-Dioxycortisol * 17-alpha-Hydroxycortexone * 17-Hydroxy-11-deoxycorticosterone * NSC-18317 * Reichstein's compound S * Reichstein's substance S * SKF 3050 * Substance S *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04684 ** MUTATION DATA ** TYPE OF TEST : DNA adduct TEST SYSTEM : Human Liver DOSE/DURATION : 2 mmol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 370,49,1996 *** END OF RECORD ***