*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TU5060000
CHEMICAL NAME           : Pregn-4-ene-3,20-dione, 17-hydroxy-
CAS REGISTRY NUMBER     : 68-96-2
BEILSTEIN REFERENCE NO. : 2062088
REFERENCE               : 4-08-00-02189 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H30-O3
MOLECULAR WEIGHT        : 330.51
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Human
                          Hormone
SYNONYMS/TRADE NAMES :
   * Gestageno gador
   * 17-Hydroxypregn-4-ene-3,20-dione
   * 17-Hydroxyprogesterone
   * 17-alpha-Hydroxyprogesterone
   * Prodix
   * Prodox
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Human - woman
DOSE                    : 65 mg/kg
SEX/DURATION            : female 8-32 week(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - gastrointestinal
   system
   Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
   PEDIAU Pediatrics.  (American Academy of Pediatrics, P.O. Box 1034,
   Evanston, IL 60204) V.1-    1948-  Volume(issue)/page/year: 26,151,1960
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 5 mg/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   ACEDAB Acta Endocrinologica, Supplementum (Copenhagen).  (Periodica,
   Skolegade 12 E, DK-2500 Valby, Denmark)  No.1-    1948-
   Volume(issue)/page/year: 28,18,1956
 
                            *** END OF RECORD ***