*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : TU5514000
CHEMICAL NAME : Pregn-4-ene-3,11,20-trione, 9-bromo-
CAS REGISTRY NUMBER : 2527-11-9
LAST UPDATED : 198910
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C21-H27-Br-O3
MOLECULAR WEIGHT : 407.39
COMPOUND DESCRIPTOR : Reproductive Effector
Human
Hormone
SYNONYMS/TRADE NAMES :
* Braxorone
* 9-alpha-Bromo-11-ketoprogesterone
* 9-Bromopregn-4-ene-3,11,20-trione
* 9-alpha-Bromopregn-4-ene-3,11,20-trione
* Pregn-4-ene-3,11,20-trione, 9-alpha-bromo-
*** HEALTH HAZARD DATA ***
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - woman
DOSE : 13 mg/kg
SEX/DURATION : female 21 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co.,
11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920-
Volume(issue)/page/year: 76,626,1958
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - woman
DOSE : 18 mg/kg
SEX/DURATION : female 15 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
OBGNAS Obstetrics and Gynecology. (Elsevier Science Pub. Co., Inc., 52
Vanderbilt Ave., New York, NY 10017) V.1- 1953- Volume(issue)/page/year:
10,411,1957
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - mouse
DOSE : 200 ug/kg
SEX/DURATION : female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of
Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877-
Volume(issue)/page/year: 71,494,1958
*** END OF RECORD ***