*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TU5560000
CHEMICAL NAME           : Pregn-4-en-3-one, 20-beta-hydroxy-
CAS REGISTRY NUMBER     : 145-15-3
LAST UPDATED            : 199206
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H32-O2
MOLECULAR WEIGHT        : 316.53
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * 20-beta-Dihydroprogesterone
   * 20-beta-Hydroxydihydroprogesterone
   * 20-beta-Hydroxypregn-4-en-3-one
   * (20R)-20-Hydroxypregn-4-en-3-one
   * 20-beta-Hydroxyprogesterone
   * 4-Pregnen-2-beta-ol-3-one
   * Pregn-4-en-3-one, 20-hydroxy-, (20-R)-
   * 20-beta-Progerol
   * Progesterol-20-beta
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 35 mg/kg
SEX/DURATION            : female 7 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
   JEMEAV Journal of Experimental Medicine.  (Rockefeller Univ. Press, 1230
   York Ave., New York, NY 10021)  V.1-    1896-  Volume(issue)/page/year:
   102,347,1955
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 5 mg/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   ACEDAB Acta Endocrinologica, Supplementum (Copenhagen).  (Periodica,
   Skolegade 12 E, DK-2500 Valby, Denmark)  No.1-    1948-
   Volume(issue)/page/year: 28,18,1956
 
                            *** END OF RECORD ***