*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TU5570270
CHEMICAL NAME           : 17-alpha-Pregn-4-en-20-yn-3-one, 17-hydroxy-, and
                          19-nor-17-alpha-pregna-1,3,5(10)-trien-
                          20-yne-3,17-diol (1:1000)
CAS REGISTRY NUMBER     : 53568-84-6
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H28-O2.C20-H24-O2
MOLECULAR WEIGHT        : 608.93
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Human
                          Hormone
SYNONYMS/TRADE NAMES :
   * Amenorone forte
   * Ethinylestradiol and ethisterone (1:1000)
   * Ethisterone and ethinylestradiol (1000:1)
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE                    : 276 mg/kg
SEX/DURATION            : female 6-38 week(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
   LANCAO Lancet.  (7 Adam St., London WC2N 6AD, UK)  V.1-    1823-
   Volume(issue)/page/year: 2,267,1958
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE                    : 3 mg/kg
SEX/DURATION            : female 5 week(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - Central Nervous System
REFERENCE :
   NATUAS Nature.  (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
   V.1-    1869-  Volume(issue)/page/year: 216,83,1967
 
                            *** END OF RECORD ***