*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TX2900000
CHEMICAL NAME           : Propane, 1,3-bis(1-aziridinylsulfonyl)-
CAS REGISTRY NUMBER     : 19218-16-7
BEILSTEIN REFERENCE NO. : 0244429
REFERENCE               : 4-20-00-00038 (Beilstein Handbook Reference)
LAST UPDATED            : 199706
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C7-H14-N2-O4-S2
MOLECULAR WEIGHT        : 254.35
WISWESSER LINE NOTATION : T3NTJ ASW3SW- AT3NTJ
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Aziridine, 1,1'-(trimethylenedisulfonyl)bis-
   * omega,omega'-Bis-(ethyleneiminosulphonyl)propane
   * 1,3-Bis(ethyleniminosulfonyl)propane
   * 1,3-Di(ethylenesulphamoyl)propane
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 80 mg/kg/I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Tumorigenic - facilitates action of known carcinogen
REFERENCE :
   ANYAA9 Annals of the New York Academy of Sciences.  (New York Academy of
   Sciences, 2 E. 63rd St., New York, NY 10021)  V.1-    1877-
   Volume(issue)/page/year: 68,750,1958
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 4 mg/kg
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 6,357,1951
 
TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 4 mg/kg
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 6,357,1951
 
                            *** END OF RECORD ***