*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TW3740000
CHEMICAL NAME           : L-Proline, 5-oxo-, 4-(acetylamino)phenyl ester
CAS REGISTRY NUMBER     : 114485-92-6
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H14-N2-O4
MOLECULAR WEIGHT        : 262.29
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-Oxo-L-proline 4-(acetylamino)phenyl ester
   * L-5-Oxopyrrolidine-2-paracetamol-carboxylate
   * Paracetamol-PGA
   * Paracetamol pyroglutamic acid ester
   * Pidolacetamol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 48,479,1996
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 48,479,1996
 
                            *** END OF RECORD ***