*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TW3780000
CHEMICAL NAME           : Proline, 5-oxo-, L-, compd. with L-arginine (1:1)
CAS REGISTRY NUMBER     : 56265-06-6
LAST UPDATED            : 198702
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C6-H14-N4-O2.C5-H7-N-O3
MOLECULAR WEIGHT        : 303.37
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Adiuvant
   * Arginina pidolato
   * Arginine pidolate
   * Arginine pyroglutamate
   * L-Arginine compd. with 5-oxo-L-proline (1:1)
   * G-278
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   17,85,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   17,85,1981
 
                            *** END OF RECORD ***