*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TX7002000
CHEMICAL NAME           : 1,3-Propanediamine,
                          N'-(benz(b)acridin-12-yl)-N,N-bis(2-chloroethyl)-,
                          dihydrochloride, hydrate
CAS REGISTRY NUMBER     : 38915-57-0
LAST UPDATED            : 199012
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H25-Cl2-N3.2Cl-H.H2-O
MOLECULAR WEIGHT        : 516.35
WISWESSER LINE NOTATION : T E6 C666 BNJ MM3N2G2G &GH 2 &QH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benz(b)acridine, 12-((3-(bis(2-chloroethyl)amino)propyl)amino)-,  
   dihydrochloride, hydrate
   * 12-((3-(Bis(2-chloroethyl)amino)propyl)amino)benz(b)acridine  
   dihydrochloride hydrate
   * ICR 417
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD20 - Lethal Dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 621 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,739,1972
 
                            *** END OF RECORD ***