*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TX7387000
CHEMICAL NAME           : 1,3-Propanediamine,
                          N,N-diethyl-N'-(9-methoxy-5,11-dimethyl-6H-pyrido(4,3
                          -b)carbazol-1-yl)-
CAS REGISTRY NUMBER     : 72238-02-9
BEILSTEIN REFERENCE NO. : 0718451
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C25-H32-N4-O
MOLECULAR WEIGHT        : 404.61
WISWESSER LINE NOTATION : T D6 B656 FN LMJ C1 EM3N2&2 J1 PO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1-((3-(Diethylamino)propyl)amino)-5,11-dimethyl-9-methoxy-6H-pyrido(4,3-
     b)carbazole
   *   1-((3-(Diethylamino)propyl)amino)-9-methoxy-5,11-dimethyl-6H-pyrido(4,3-
     b)carbazole
   *   N,N-Diethyl-N'-(9-methoxy-5,11-dimethyl-6H-pyrido(4,3-b)carbazol-1-yl)-1
     ,3-propanediamine
   * 6H-Pyrido(4,3-b)carbazole,  
   1-((3-diethylamino)propylamino)-5,11-dimethyl-9-methoxy-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,181,1983
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 23,1212,1980
 
                            *** END OF RECORD ***