*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TY7600000 CHEMICAL NAME : 1,3-Propanediol, 2-(hydroxymethyl)-2-phenyl-, cyclic phosphate (1:1) CAS REGISTRY NUMBER : 2200-87-5 BEILSTEIN REFERENCE NO. : 2278548 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C10-H11-O4-P MOLECULAR WEIGHT : 226.18 WISWESSER LINE NOTATION : T66 A B AO EOPOTJ CR& FO COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 2-(Hydroxymethyl)-2-phenyl-1,3-propanediol, cyclic phosphate (1:1) * 4-Phenyl-2,6,7-trioxa-1-phosphabicyclo(2.2.2)octan-1-one * 2,6,7-Trioxa-1-phosphabicyclo(2.2.2)octan-1-one, 4-phenyl- *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1500 ug/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Behavioral - ataxia REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 36,261,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 690 ug/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - changes in structure or function of salivary glands REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 13,207,1978 *** END OF RECORD ***