*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TY3161000
CHEMICAL NAME           : 1,2-Propanediol, 3-(6-amino-9H-purin-9-yl)-, (R,S)-
CAS REGISTRY NUMBER     : 55904-02-4
LAST UPDATED            : 199706
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C8-H11-N5-O2
MOLECULAR WEIGHT        : 209.24
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * (R,S)-3-(6-Amino-9H-purin-9-yl)-1,2-propanediol
   * (RS)-Dhpa
   * (R,S)-9-(2,3-Dihydroxypropyl)adenine
   * 1,2-Propanediol, 3-(6-amino-9H-purin-9-yl)-, (+-)-
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Specific locus test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 1000 ppm
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 311,305,1994
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - rabbit Kidney
DOSE/DURATION           : 311 mg/L
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 28,282,1985
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - rabbit Kidney
DOSE/DURATION           : 376 mg/L
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 28,282,1985
 
                            *** END OF RECORD ***