*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TZ0576000
CHEMICAL NAME           : 1,2-Propanediol,
                          3-((6-methyl-5H-pyrido(3',4':4,5)pyrrolo(2,3-g)isoqui
                          nolin-10-yl)amino)-
CAS REGISTRY NUMBER     : 83948-01-0
BEILSTEIN REFERENCE NO. : 5612652
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H18-N4-O2
MOLECULAR WEIGHT        : 322.40
WISWESSER LINE NOTATION : T D6 B656 FN LM PNJ EM1YQ1Q
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   3-((6-Methyl-5H-pyrido(3',4':4,5)pyrrolo(2,3-g)isoquinolin-10-yl)amino)-
     1,2-propanediol
   * 5H-Pyrido(3',4':4,5)pyrrolo(2,3-g)isoquinoline, 1,2-propanediol deriv.
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,181,1983
 
                            *** END OF RECORD ***