*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : TZ0800000
CHEMICAL NAME : 1,2-Propanediol, 3-(1-naphthyloxy)-
CAS REGISTRY NUMBER : 36112-95-5
LAST UPDATED : 199012
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C13-H14-O3
MOLECULAR WEIGHT : 218.27
WISWESSER LINE NOTATION : L66J BO1YQ1Q
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 1-(2,3-Dihydroxypropoxy)naphthalene
* Naphthalene, 1-(2,3-dihydroxypropoxy)-
* 3-(alpha-Naphthoxy)-1,2-propanediol
* Propanolol glycol
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 6900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 7,167,1964
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 828 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
(usually neuromuscular blockage)
Behavioral - muscle weakness
Lungs, Thorax, or Respiration - other changes
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 93,470,1948
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 88 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 188,86,1974
*** END OF RECORD ***