*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TZ0819000
CHEMICAL NAME           : 1,3-Propanediol,
                          2-((2-nitro-1H-imidazol-1-yl)methoxy)-
CAS REGISTRY NUMBER     : 120398-89-2
LAST UPDATED            : 199409
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C7-H11-N3-O5
MOLECULAR WEIGHT        : 217.21
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-((2-Nitro-1H-imidazol-1-yl)methoxy)-1,3-propanediol
   * RP-170
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JKXXAF Japanese Kokai Tokyo Koho Patents.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year:
   #91-209323
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB
   211, 1000 AE Amsterdam, Netherlands)  V.76-    1985-
   Volume(issue)/page/year: 80,1113,1989
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 4300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTKRDX Gan to Kagaku Ryoho.  Cancer and Chemotherapy.  (1-8-9 Yaesu,
   Chuo-ku, Tokyo 103, Japan) V.1-    1974-  Volume(issue)/page/year:
   16,1399,1989
 
                            *** END OF RECORD ***