*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TZ1200000
CHEMICAL NAME           : 1,2-Propanediol, 3-(m-tolyloxy)-
CAS REGISTRY NUMBER     : 621-24-9
BEILSTEIN REFERENCE NO. : 1948930
REFERENCE               : 4-06-00-02044 (Beilstein Handbook Reference)
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H14-O3
MOLECULAR WEIGHT        : 182.24
WISWESSER LINE NOTATION : Q1YQ1OR C1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * m-Mephenesin
   * 1,2-Propanediol, 3-(3-methylphenoxy)-
   * 3-(m-Tolyloxy)-1,2-propanediol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 72,1545,1952
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1474 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 93,470,1948
 
                            *** END OF RECORD ***