*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TZ3150000 CHEMICAL NAME : Propane, 1,3-epoxy-2,2-dimethyl- CAS REGISTRY NUMBER : 6921-35-3 BEILSTEIN REFERENCE NO. : 0102430 REFERENCE : 5-17-01-00085 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C5-H10-O MOLECULAR WEIGHT : 86.15 WISWESSER LINE NOTATION : T4OTJ C1 C1 COMPOUND DESCRIPTOR : Tumorigen Drug SYNONYMS/TRADE NAMES : * 3,3-Dimethyloxetane * beta,beta-Dimethyltrimethylene oxide * 3,3-Dimethyltrimethylene oxide * 1,3-Epoxy-2,2-dimethylpropane * Oxetane, 3,3-dimethyl- *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Behavioral - general anesthetic REFERENCE : JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 1,355,1959 ** TUMORIGENIC DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1020 mg/kg/61W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application REFERENCE : BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 17,100,1963 *** REVIEWS *** TOXICOLOGY REVIEW 22HAAD "Microbial Toxins, 1970-72," Ajil, S.J., et al., eds., New York, Academic Press, Inc., 1970-72 Volume(issue)/page/year: 6,409,1971 *** END OF RECORD ***