*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TY3192000
CHEMICAL NAME           : 1,3-Propanediol,
                          2-((4,6-bis(1-aziridinyl)-s-triazin-2-yl)amino)-
CAS REGISTRY NUMBER     : 60819-41-2
BEILSTEIN REFERENCE NO. : 0552351
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H16-N6-O2
MOLECULAR WEIGHT        : 252.32
WISWESSER LINE NOTATION : T6N CN ENJ BMY1Q1Q D- AT3NTJ& F- AT3NTJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-((4,6-Bis(1-aziridinyl)-s-triazin-2-yl)amino)-1,3-propanediol
   * 2-(4,6-Diaziridinyl-2-s-triazinylamino)-1,3-propanediol
   * 6-(1,3-Dihydroxy-2-propylamino)-2,4-di(ethyleneimino)triazine
   * 1,3-Propanediol, 2-((4,6-bis(1-aziridinyl)-1,3,5-triazin-2-yl)amino)-
   * 1,3-Propanediol, 2-(4,6-diaziridinyl-2-s-triazinylamino)-
   * s-Triazine, 4,6-diaziridinyl-2-(1,3-dihydroxy-2-propylamino)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3002 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JSONDX Journal of Soviet Oncology.  (New York, NY)  V.1-5, 1980-84.
   Volume(issue)/page/year: 1,239,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7493 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 12,481,1978
 
                            *** END OF RECORD ***