*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TY3192300
CHEMICAL NAME           : 1,3-Propanediol,
                          2-((4,6-bis(1-aziridinyl)-s-triazin-2-yl)amino)-2-eth
                          yl-
CAS REGISTRY NUMBER     : 60819-43-4
BEILSTEIN REFERENCE NO. : 0556908
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H20-N6-O2
MOLECULAR WEIGHT        : 280.38
WISWESSER LINE NOTATION : T6N CN ENJ BMX2&1Q1Q D- AT3NTJ& F- AT3NTJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-((4,6-Bis(1-aziridinyl)-s-triazin-2-yl)amino)-2-ethyl-1,3-propanediol
   * 2-(4,6-Diaziridinyl-2-s-triazinylamino)-2-ethyl-1,3-propanediol
   * 6-(1-(1,2-Dihydroxymethyl)propylamino)-2,4-di(ethylimino)triazine
   * 1,3-Propanediol,  
   2-((4,6-bis(1-aziridinyl)-1,3,5-triazin-2-yl)amino)-2-ethyl-
   * 1,3-Propanediol, 2-(4,6-diaziridinyl-2-s-triazinylamino)-2-ethyl-
   * s-Triazine, 2,4-diaziridinyl-6-(1-hydroxy-2-hydroxymethyl-2-butylamino)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   VOONAW Voprosy Onkologii.  Problems of Oncology.  For English translation,
   see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-10,
   1928-37; V.1-    1955-  Volume(issue)/page/year: 23(12),70,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 11 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 12,481,1978
 
                            *** END OF RECORD ***