*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TY3192800 CHEMICAL NAME : 1,3-Propanediol, 2-((4,6-bis(1-aziridinyl)-s-triazin-2-yl)amino)-2-met hyl- CAS REGISTRY NUMBER : 60819-42-3 BEILSTEIN REFERENCE NO. : 0554214 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C11-H18-N6-O2 MOLECULAR WEIGHT : 266.35 WISWESSER LINE NOTATION : T6N CN ENJ BMX1&1Q1Q D- AT3NTJ& F- AT3NTJ COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 2-((4,6-Bis(1-aziridinyl)-s-triazin-2-yl)amino)-2-methyl-1,3-propanediol * 2-((4,6-Bis(1-aziridinyl)-1,3,5-triazin-2-yl)amino)-2-methyl-1,3-propane diol * 2-(4,6-Diaziridinyl-2-s-triazinylamino)-2-methyl-1,3-propanediol * 6-(1-(1,2-Dihydroxymethyl)ethylamino)-2,4-di(ethyleneimino)triazine * 1,3-Propanediol, 2-(4,6-diaziridinyl-2-s-triazinylamino)-2-methyl- * s-Triazine, 2,4-diaziridinyl-6-(1,3-dihydroxy-2-methyl-2-propylamino)- *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 8 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : VOONAW Voprosy Onkologii. Problems of Oncology. For English translation, see PONCAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1928-37; V.1- 1955- Volume(issue)/page/year: 23(12),70,1977 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 13 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 12,481,1978 *** END OF RECORD ***