*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TZ5550000
CHEMICAL NAME           : Propane, 1,1,2,2,3-pentachloro-
CAS REGISTRY NUMBER     : 16714-68-4
BEILSTEIN REFERENCE NO. : 1738270
REFERENCE               : 4-01-00-00204 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C3-H3-Cl5
MOLECULAR WEIGHT        : 216.31
WISWESSER LINE NOTATION : GYGXGG1G
SYNONYMS/TRADE NAMES :
   * 1,1,2,2,3-Pentachloropropane
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 819 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Blood - other changes
REFERENCE :
   TKGMB8 Trudy Khar'kovskogo Meditsinskogo Instituta.  (Khar'kovskii
   Gosudarstvennyi Meditsinskii Institut, Kharkov, USSR) N.1- 1935-
   Volume(issue)/page/year: 124,27,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 551 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Blood - other changes
REFERENCE :
   TKGMB8 Trudy Khar'kovskogo Meditsinskogo Instituta.  (Khar'kovskii
   Gosudarstvennyi Meditsinskii Institut, Kharkov, USSR) N.1- 1935-
   Volume(issue)/page/year: 124,27,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Blood - other changes
REFERENCE :
   TKGMB8 Trudy Khar'kovskogo Meditsinskogo Instituta.  (Khar'kovskii
   Gosudarstvennyi Meditsinskii Institut, Kharkov, USSR) N.1- 1935-
   Volume(issue)/page/year: 124,27,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 560 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Blood - other changes
REFERENCE :
   TKGMB8 Trudy Khar'kovskogo Meditsinskogo Instituta.  (Khar'kovskii
   Gosudarstvennyi Meditsinskii Institut, Kharkov, USSR) N.1- 1935-
   Volume(issue)/page/year: 124,27,1976
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 281 ppm/6H/4W-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in bladder weight
   Related to Chronic Data - death
   Related to Chronic Data - changes in ovarian weight
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 25,317,1988
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 15 ppm/6H/13W-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in bladder weight
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 25,317,1988

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***