*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TZ7800000
CHEMICAL NAME           : Propanethiol, trimethoxysilyl-
CAS REGISTRY NUMBER     : 4420-74-0
BEILSTEIN REFERENCE NO. : 2038119
LAST UPDATED            : 199712
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C6-H16-O3-S-Si
MOLECULAR WEIGHT        : 196.37
WISWESSER LINE NOTATION : SH3-SI-O1&O1&O1
COMPOUND DESCRIPTOR     : Organometallic
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * A 189 (silicone)
   * AZ 6129
   * GF 70
   * KBE 803
   * KBM 803
   * M 8500
   * gamma-Mercaptopropyltrimethoxysilane
   * 3-Mercaptopropyltrimethoxysilane
   * MPS
   * NUCA 189
   * Prosil 196
   * SH 6062
   * Sila-Ace S 810
   * Silane A 189
   * Silane, 3-mercaptopropyltrimethoxy-
   * Silicone A-189
   * Silquest A 189
   * 3-(Trimethoxysilyl)propanethiol
   * TSL8380E
   * Union carbide A-189
   * Z 6062
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Open irritation test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg
REACTION SEVERITY       : Mild
REFERENCE :
   UCDS** Union Carbide Data Sheet.  (Union Carbide Corp., 39 Old Ridgebury
   Rd., Danbury, CT 06817)  Volume(issue)/page/year: 4/2/1971
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2830 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   30,470,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 633 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DANKAS Doklady Akademii Nauk SSSR.  Proceedings of the Academy of Sciences
   of the USSR.  For English translation, see DBIOAM and DKBSAS.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-    1933-
   Volume(issue)/page/year: 229,1011,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 5660 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   30,470,1969

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X1504
       No. of Facilities: 27 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 81 (estimated)
       No. of Female Employees: 27 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***