*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UA2465700
CHEMICAL NAME           : Propanoic acid, 2-hydroxy-, compd. with
                          2,2'-(1,3-propanediylbis(oxy(3-methoxy-4,1-
                          phenylene)))bis(4,5-dihydro-1H-imidazole) (2:1)
CAS REGISTRY NUMBER     : 152368-25-7
LAST UPDATED            : 199509
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H28-N-O4.C6-H12-O6
MOLECULAR WEIGHT        : 562.70
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,3-Di(4-imidazolino-2-methoxyphenoxy)propane lactate
   * 1H-Imidazole,  
   2,2'-(1,3-propanediylbis(oxy(3-methoxy-4,1-phenylene)))bis(4,5-dihydro-,  
   lactate
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 112 mg/kg/28D-I
TOXIC EFFECTS :
   Behavioral - tremor
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - phosphatases
REFERENCE :
   DRUIEA Drug Investigation.  (ADIS International Ltd., Private Bag 65901,
   Mairangi Bay, Auckland 10, New Zealand)  V.1-    1989-
   Volume(issue)/page/year: 6,311,1993
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 116 mg/kg/29D-I
TOXIC EFFECTS :
   Behavioral - tremor
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - multiple enzyme effects
REFERENCE :
   DRUIEA Drug Investigation.  (ADIS International Ltd., Private Bag 65901,
   Mairangi Bay, Auckland 10, New Zealand)  V.1-    1989-
   Volume(issue)/page/year: 6,311,1993
 
                            *** END OF RECORD ***