*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UA7254000
CHEMICAL NAME           : 2-Propanol,
                          1-(1,2-benzisothiazol-4-yloxy)-3-isopropylamino-,
                          hydrochloride
CAS REGISTRY NUMBER     : 67982-19-8
LAST UPDATED            : 199406
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H18-N2-O2-S.Cl-H
MOLECULAR WEIGHT        : 302.85
WISWESSER LINE NOTATION : T56 BSNJ FO1YQ1MY1&1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(1,2-Benzisothiazol-4-yloxy)-3-isopropylamino-2-propanol hydrochloride
   * 4-(2-Hydroxy-3-isopropylaminopropoxy)-1,2-benzisothiazole  
   monohydrochloride
   * LU 24329
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 142 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - beta-adrenergic blockage
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 30,1831,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 62100 ug/kg
TOXIC EFFECTS :
   Autonomic Nervous System - beta-adrenergic blockage
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 30,1831,1980
 
                            *** END OF RECORD ***