*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UA8987000
CHEMICAL NAME           : 2-Propanol,
                          1-(3-((2-chloro-6,7-dimethoxy-4-quinazolinyl)amino)ph
                          enoxy)-3-((1-methylet hyl) amino)-, dihydrochloride,
                          hydrate
CAS REGISTRY NUMBER     : 111218-79-2
LAST UPDATED            : 198906
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H27-Cl-N4-O4.2Cl-H.H2-O
MOLECULAR WEIGHT        : 536.91
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethox
     yquinazoline 2HCl H2O
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 64 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 21,478,1987
 
                            *** END OF RECORD ***