*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UA9893000
CHEMICAL NAME           : 2-Propanol,
                          1-((3-dibenzo(b,e)thiepin-11(6H)-ylidenepropyl)methyl
                          amino)-, hydrochloride, (E)-
CAS REGISTRY NUMBER     : 85196-08-3
LAST UPDATED            : 198702
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H25-N-O-S.Cl-H
MOLECULAR WEIGHT        : 375.99
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   (E)-1-((3-Dibenzo(b,e)thiepin-11(6H)-ylidenepropyl)methylamino)-2-propan
     ol hydrochloride
   *   (E)-11-(3-(N-(2-Hydroxypropyl)-N-methylamino)propylidene)-6,11-dihydrodi
     benzo(b,e)thiepin HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 554 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 48,163,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 22700 ug/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 48,163,1983
 
                            *** END OF RECORD ***