*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UB3690000 CHEMICAL NAME : 2-Propanol, 1-(dimethylamino)-3-(4-(2,4,7-triamino-6-pteridinyl)p henoxy)- CAS REGISTRY NUMBER : 96558-24-6 BEILSTEIN REFERENCE NO. : 4273708 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C17-H22-N8-O2 MOLECULAR WEIGHT : 370.47 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 4'-(3-Dimethylamino-2-hydroxypropoxy)triamterene * 1-(Dimethylamino)-3-(4-(2,4,7-triamino-6-pteridinyl)phenoxy)-2-propanol * RPH 2823 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >741 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 50,419,1995 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 21855 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 50,419,1995 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 22 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 35,1688,1985 *** END OF RECORD ***