*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UB3773700
CHEMICAL NAME           : 2-Propanol,
                          1-((1,1-dimethylethyl)amino)-3-((3-methyl-1,2-benziso
                          xazol-4-yl)oxy)-
CAS REGISTRY NUMBER     : 63152-60-3
BEILSTEIN REFERENCE NO. : 1219463
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H22-N2-O3
MOLECULAR WEIGHT        : 278.39
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1-((1,1-Dimethylethyl)amino)-3-((3-methyl-1,2-benzisoxazol-4-yl)oxy)-2-p
     ropanol
   * LU 24943
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 215 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - beta-adrenergic blockage
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 30,1831,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 197 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - beta-adrenergic blockage
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 30,1831,1980
 
                            *** END OF RECORD ***