*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UC0175000 CHEMICAL NAME : 2-Propanol, 1,1,1-trichloro-2-methyl- CAS REGISTRY NUMBER : 57-15-8 BEILSTEIN REFERENCE NO. : 0878167 REFERENCE : 4-01-00-01629 (Beilstein Handbook Reference) LAST UPDATED : 199701 DATA ITEMS CITED : 8 MOLECULAR FORMULA : C4-H7-Cl3-O MOLECULAR WEIGHT : 177.46 WISWESSER LINE NOTATION : QX1&1&XGGG COMPOUND DESCRIPTOR : Drug Mutagen Primary Irritant SYNONYMS/TRADE NAMES : * Acetone chloroform * Anhydrous chlorobutanol * Chlorbutanol * Chlorbutol * Chloretone * Chlorobutanol * Chlorobutanol, anhydrous * Clortran * Coliquifilm * Methaform * 2-Propanol, 2-methyl-1,1,1-trichloro- * Sedaform * Trichloro-tert-butanol * Trichloro-t-butyl alcohol * beta,beta,beta-Trichloro-tert-butyl alcohol * t-Trichlorobutyl alcohol * HCP * 1,1,1-Trichloro-2-methyl-2-propanol *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 850 ug REACTION SEVERITY : Mild REFERENCE : XEURAQ U.S. Atomic Energy Commission, University of Rochester, Research and Development Reports. (Rochester, NY) Volume(issue)/page/year: MDDC-1715 TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 9180 ug/30S REACTION SEVERITY : Mild REFERENCE : XEURAQ U.S. Atomic Energy Commission, University of Rochester, Research and Development Reports. (Rochester, NY) Volume(issue)/page/year: MDDC-1715 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 238 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - other changes REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 8,77,1901 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 213 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 8,77,1901 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Parenteral SPECIES OBSERVED : Amphibian - frog DOSE/DURATION : 800 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Vascular - regional or general arteriolar or venous dilation Lungs, Thorax, or Respiration - other changes REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 8,77,1901 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 20 umol/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 90,91,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1007 No. of Facilities: 798 (estimated) No. of Industries: 3 No. of Occupations: 13 No. of Employees: 25038 (estimated) No. of Female Employees: 21000 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***