*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UC0230000
CHEMICAL NAME           : 1-Propanol, 3-(trimethoxysilyl)-, methacrylate
CAS REGISTRY NUMBER     : 2530-85-0
BEILSTEIN REFERENCE NO. : 1952435
LAST UPDATED            : 199710
DATA ITEMS CITED        : 12
MOLECULAR FORMULA       : C10-H20-O5-Si
MOLECULAR WEIGHT        : 248.39
WISWESSER LINE NOTATION : 1UY1&VO3-SI-O1&O1&O1
COMPOUND DESCRIPTOR     : Primary Irritant
SYNONYMS/TRADE NAMES :
   * Dynasylan MEMO
   * KBM 503
   * KH 570
   * M 8550
   * Methacrylic acid, 3-(trimethoxysilyl)propyl ester
   * gamma-Methacryloxypropyltrimethoxysilane
   * Mops-M
   * NUCA 174
   * 2-Propenoic acid, 2-methyl-, 3-(trimethoxysilyl)propyl ester
   * Silane, (3-hydroxypropyl)trimethoxy-, methacrylate
   * Silicone A-174
   * 3-(Trimethoxysilyl)-1-propanol methacrylate
   * Trimethoxysilyl-3-propylester kyseliny methakrylove
   * Union carbide A-174
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/24H
REACTION SEVERITY       : Mild
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,1235,1986
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/24H
REACTION SEVERITY       : Mild
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,1235,1986
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 22600 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   UCDS** Union Carbide Data Sheet.  (Union Carbide Corp., 39 Old Ridgebury
   Rd., Danbury, CT 06817)  Volume(issue)/page/year: 11/9/1967
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 226 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NKOGAV Nippon Kokoka Gakkai Zasshi.  Journal of the Japanese Stomatological
   Society.  (Nippon Kokoka Gakkai, c/o Tokyo Daigaku Igakubu Koko Gekagaku
   Kyoshitsu, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113, Japan)  V.1-    1952-
   Volume(issue)/page/year: 22,533,1973
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >20 mL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   UCDS** Union Carbide Data Sheet.  (Union Carbide Corp., 39 Old Ridgebury
   Rd., Danbury, CT 06817)  Volume(issue)/page/year: 11/9/1967
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 143 mg/m3/6H/4W-I
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0529951

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - T0118
       No. of Facilities: 64 (estimated)
       No. of Industries: 3
       No. of Occupations: 6
       No. of Employees: 966 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - T0118
       No. of Facilities: 2492 (estimated)
       No. of Industries: 36
       No. of Occupations: 27
       No. of Employees: 31238 (estimated)
       No. of Female Employees: 7749 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   47,26992,82

   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***