*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UB6500000
CHEMICAL NAME           : 2-Propanol,
                          1-(4-hydroxy-2,3,5-trimethylphenoxy)-3-(isopropylamin
                          o)-, 4-acetate
CAS REGISTRY NUMBER     : 22664-55-7
OTHER CAS REGISTRY NOS. : 38202-74-3
BEILSTEIN REFERENCE NO. : 2152010
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H27-N-O4
MOLECULAR WEIGHT        : 309.45
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Disorat
   * 4-(2-Hydroxy-3-((1-methylethyl)-amino)propoxy)-2,3,6-trimethylphenol  
   1-acetate
   * 1-(4-Hydroxy-2,3,5-trimethylphenoxy)-3-(isopropylamino)-2-propanol  
   4-acetate
   * Methypranol
   * Metipranolol
   * Phenol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-2,3,6-trimethyl-,  
   1-acetate
   * Trimepranol
   * VUFB-6453
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 50,2289,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 31 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 27,1022,1977
 
                            *** END OF RECORD ***