*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UC2984000 CHEMICAL NAME : 1-Propanone, 1-(4-(2-hydroxy-3-(4-phenyl-1-piperazinyl)propoxy)phe nyl)- CAS REGISTRY NUMBER : 34675-77-9 BEILSTEIN REFERENCE NO. : 0578135 REFERENCE : 5-23-02-00114 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C22-H28-N2-O3 MOLECULAR WEIGHT : 368.52 WISWESSER LINE NOTATION : T6N DNTJ A1YQ1OR DV2& DR COMPOUND DESCRIPTOR : Drug Human SYNONYMS/TRADE NAMES : * Centropazine * 1-(4-(2-Hydroxy-3-(4-phenyl-1-piperazinyl)propoxy)phenyl)-1-propanone * 4'-(2-Hydroxy-3-(4-phenylpiperazin-1-yl)propoxy)propiophenone * 3-(4-Phenylpiperazinyl)-1-(4-propionylphenoxy)propan-2-ol * Propiophenone, 4'-(2-hydroxy-3-(4-phenylpiperazinyl)propoxy)- * 1-(p-Propionylphenoxy)-3-(4-phenylpiperazinyl)-2-propanol *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human DOSE/DURATION : 1710 ug/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 5,338,1980 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 270 mg/kg TOXIC EFFECTS : Behavioral - wakefulness REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 15,286,1972 *** END OF RECORD ***