*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UC3916000
CHEMICAL NAME           : 1H,6H-5,10b-Propanophenanthridin-9-ol,
                          2,3,4,4a-tetrahydro-, hydrochloride
CAS REGISTRY NUMBER     : 3737-01-7
LAST UPDATED            : 198406
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H21-N-O.Cl-H
MOLECULAR WEIGHT        : 279.84
WISWESSER LINE NOTATION : T6 G666/FQ 2AF Q FX NNT&TTJ IQ &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 9-Aza-des-N-morphinan
   * DH 7
   * 6-Hydroxy-4a,10-trimethylene-1,2,3,4,4a,9,10,10a-octahydrophenanthridine  
   hydrochloride
   * 2,3,4,4a-Tetrahydro-1H,6H-5,10b-propanophenanthridin-9-ol hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JJPAAZ Japanese Journal of Pharmacology.  (Japanese Pharmacological Soc.,
   c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto
   606, Japan)  V.1-    1951-  Volume(issue)/page/year: 11,101,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 11,489,1963
 
                            *** END OF RECORD ***