*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UD0175000
CHEMICAL NAME           : Propene, hexachloro-
CAS REGISTRY NUMBER     : 1888-71-7
BEILSTEIN REFERENCE NO. : 1766640
REFERENCE               : 4-01-00-00753 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 9
MOLECULAR FORMULA       : C3-Cl6
MOLECULAR WEIGHT        : 248.73
WISWESSER LINE NOTATION : GYGUYGXGGG
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Hexachloropropene
   * Hexachloropropylene
   * RCRA waste number U243
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 425 ppm/30M
TOXIC EFFECTS :
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
   Liver - hepatitis (hepatocellular necrosis), diffuse
REFERENCE :
   XEURAQ U.S. Atomic Energy Commission, University of Rochester, Research and
   Development Reports. (Rochester, NY)  Volume(issue)/page/year: MDDC-1715
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 400 uL/kg
TOXIC EFFECTS :
   Liver - hepatitis (hepatocellular necrosis), diffuse
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
REFERENCE :
   XEURAQ U.S. Atomic Energy Commission, University of Rochester, Research and
   Development Reports. (Rochester, NY)  Volume(issue)/page/year: MDDC-1715
 
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 ppm/30M
TOXIC EFFECTS :
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   XEURAQ U.S. Atomic Energy Commission, University of Rochester, Research and
   Development Reports. (Rochester, NY)  Volume(issue)/page/year: MDDC-1715
 
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 85 ppm/30M
TOXIC EFFECTS :
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   XEURAQ U.S. Atomic Energy Commission, University of Rochester, Research and
   Development Reports. (Rochester, NY)  Volume(issue)/page/year: MDDC-1715
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 15 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 170,1,1986

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X6277
       No. of Facilities: 7 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 1822 (estimated)
       No. of Female Employees: 272 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***