*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UE8800000
CHEMICAL NAME           : Propionic acid,
                          2-((4'-chloro-4-biphenylyl)oxy)-2-methyl-, methyl
                          ester
CAS REGISTRY NUMBER     : 21340-68-1
BEILSTEIN REFERENCE NO. : 2139378
LAST UPDATED            : 199801
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H17-Cl-O3
MOLECULAR WEIGHT        : 304.79
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * ICI 54856 methyl ester
   * Methyl-2-(4-(p-chlorophenyl)phenoxy)-2-methylpropionate
   * Methyl clofenapate
   * Propanoic acid, 2-((4'-chloro(1,1'-biphenyl)-4-yl)oxy)-2-methyl-, methyl  
   ester
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 31500 mg/kg/75W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Liver - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   42,259,1982
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - hamster Embryo
DOSE/DURATION           : 50 umol/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 18,701,1997
 
                            *** END OF RECORD ***