*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UF2032500
CHEMICAL NAME           : Propionic acid, 2,2-diphenyl-, 2-(diethylamino)ethyl
                          ester
CAS REGISTRY NUMBER     : 3563-01-7
BEILSTEIN REFERENCE NO. : 2509326
REFERENCE               : 4-09-00-02535 (Beilstein Handbook Reference)
LAST UPDATED            : 199707
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H27-N-O2
MOLECULAR WEIGHT        : 325.49
WISWESSER LINE NOTATION : 2N2&2OVX1&R&R
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Aprofen
   * Aprophen
   * Benzeneacetic acid, alpha-methyl-alpha-phenyl-, 2-(diethylamino)ethyl  
   ester
   * 2-Diethylaminoethyl 2,2-diphenylpropionate
   * alpha,alpha-Diphenylpropionic acid beta-diethylaminoethyl ester
   * alpha,alpha-Diphenylpropionic acid 2-diethylaminoethyl ester
   * 2,2-Diphenylpropionic acid 2-diethylaminoethyl ester
   * alpha-Methyl-alpha-phenylbenzeneacetic acid 2-(diethylamino)ethyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 4,7,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 370 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 31,53,1968
 
                            *** END OF RECORD ***