*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UH4429200
CHEMICAL NAME           : Propiophenone,
                          2',4',6'-trihydroxy-3-(p-hydroxyphenyl)-, phosphate,
                          polyesters
CAS REGISTRY NUMBER     : 9014-72-6
LAST UPDATED            : 199312
DATA ITEMS CITED        : 3
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * AHly
   * LEO 101
   * LEO 1259a
   * LEO 1261a
   * LEO 1235g
   * LEO 101K
   * Polyphloretin phosphate
   * 1-Propanone, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-, phosphate,  
   homopolymer
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 42,660,1990
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 100 mg/kg
SEX/DURATION            : female 1 day(s) pre-mating
                          female 1 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   ACENA7 Acta Endocrinologica (Copenhagen).  (Periodica, Skolegade 12 E,
   DK-2500 Valby, Denmark) V.1-    1948-  Volume(issue)/page/year: 37,298,1961
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 100 mg/kg
SEX/DURATION            : female 16 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   PRGLBA Prostaglandins.  (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022)
   V.1-    1972-  Volume(issue)/page/year: 1,191,1972
 
                            *** END OF RECORD ***