*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UK7893600
CHEMICAL NAME           : Prosta-5,13-dien-1-oic acid,
                          2,2-difluoro-9,11,15-trihydroxy-15-methyl-,
                          theta-lactone, (5Z,9-alpha,11-alpha,13E,15S)-
CAS REGISTRY NUMBER     : 62443-67-8
BEILSTEIN REFERENCE NO. : 5630294
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H32-F2-O4
MOLECULAR WEIGHT        : 386.53
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * (15S)-2,2-Difluoro-15-methyl-pgf2-alpha 1,9-lactone
   * (15S)-2,2-Difluoro-15-methyl-prostaglandin F2-alpha 1,9-lactone
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - hamster
DOSE                    : 80 ug/kg
SEX/DURATION            : female 4 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,1089,1983
 
                            *** END OF RECORD ***