*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UK8020600 CHEMICAL NAME : Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, lambda-lactone, (5Z,9-alpha,11-alpha, 13E,15S)- CAS REGISTRY NUMBER : 55314-49-3 BEILSTEIN REFERENCE NO. : 1262372 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C20-H32-O4 MOLECULAR WEIGHT : 336.52 COMPOUND DESCRIPTOR : Reproductive Effector SYNONYMS/TRADE NAMES : * PGF2-alpha 1,15-lactone * Prostaglandin F2-alpha 1,15-lactone * U 47473 *** HEALTH HAZARD DATA *** ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Primate - monkey DOSE : 4 mg/kg SEX/DURATION : female 1 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - menstrual cycle changes or disorders REFERENCE : PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 14,477,1977 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - hamster DOSE : 800 ug/kg SEX/DURATION : female 4 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,1089,1983 *** END OF RECORD ***