*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UK8428500
CHEMICAL NAME           : Prost-5-en-13-yn-1-oic acid,
                          15-hydroxy-16-methyl-9-oxo-, methyl ester,
                          (5Z,15S,16S)-
CAS REGISTRY NUMBER     : 89648-76-0
LAST UPDATED            : 199109
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H34-O4
MOLECULAR WEIGHT        : 362.56
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 11-Deoxy-13,14-didehydro-16(S)-methylprostaglandin E2 methyl ester
   * FCE-20700
   * (5Z,15S,16S)-15-Hydroxy-16-methyl-9-oxoprost-5-en-13-yn-1-oic acid methyl 
    ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 338 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   10,737,1985
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   10,737,1985
 
                            *** END OF RECORD ***