*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UO7452000
CHEMICAL NAME           : Purine-7-acetic acid,
                          1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-, compd.
                          with 7-(2- (dimethylamino)ethoxy)flavone (1:1)
CAS REGISTRY NUMBER     : 1715-55-5
LAST UPDATED            : 198806
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C19-H19-N-O3.C9-H10-N4-O4
MOLECULAR WEIGHT        : 547.62
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Aperflavon
   * 7-(beta-Dimethylaminoaethoxy)flavon theophyllin-7-essigsaeure
   * 1,3-Dimethylxanthine-7-acetic acid 7-(beta-dimethyl)(aminoethoxy)flavon
   * FLA 10 TH
   * Laoflavon
   * Perflavon
   * Perflavone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4130 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 19,116,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2570 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 19,116,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1240 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   ABMGAJ Acta Biologica et Medica Germanica.  (Berlin, Ger. Dem. Rep.) V.1-41,
   1958-82.  For publisher information, see BBIADT. Volume(issue)/page/year:
   14,336,1965
 
                            *** END OF RECORD ***