*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BV8063500
CHEMICAL NAME           : 5-alpha-Androstan-3-one,
                          17-beta-hydroxy-2-alpha-methyl-
CAS REGISTRY NUMBER     : 58-19-5
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H32-O2
MOLECULAR WEIGHT        : 304.52
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * Androstan-3-one, 17-hydroxy-2-methyl-, (2-alpha,5-alpha,17-beta)-
   * Dihydro-2-alpha-methyltestosterone
   * Dromostanolone
   * Drostanolone
   * 17-beta-Hydroxy-2-alpha-methyl-5-alpha-androstan-3-one
   * Medrosteron
   * Metholone
   * 2-alpha-Methyldihydrotestosterone
   * 2-alpha-Methyl-17-beta-hydroxy-5-alpha-androstan-3-one
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 2 mg/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
   85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press,
   1965  Volume(issue)/page/year: -,150,1965
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 30 mg/kg
SEX/DURATION            : female 1-3 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   AJOGAH American Journal of Obstetrics and Gynecology.  (C.V. Mosby Co.,
   11830 Westline Industrial Dr., St. Louis, MO 63146)  V.1-    1920-
   Volume(issue)/page/year: 117,167,1973
 
                            *** END OF RECORD ***