*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : BV8071500 CHEMICAL NAME : 5-alpha-Androstan-3-one, 17-beta-hydroxy-, propionate CAS REGISTRY NUMBER : 855-22-1 BEILSTEIN REFERENCE NO. : 2628403 REFERENCE : 3-08-00-00576 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C22-H34-O3 MOLECULAR WEIGHT : 346.56 WISWESSER LINE NOTATION : L E5 B666 OVTJ A1 E1 FOV2 COMPOUND DESCRIPTOR : Reproductive Effector Hormone SYNONYMS/TRADE NAMES : * Androstanolone propionate * Androstan-3-one, 17-(1-oxopropoxy)-, (5-alpha,17-beta)- * DHTP * Dihydrotestosterone propionate * Dihydrotestosterone 17-beta-propionate * 5-alpha-Dihydrotestosterone propionate * (5-alpha,17-beta)-17-(1-Oxopropoxy)androstan-3-one *** HEALTH HAZARD DATA *** ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE : 50 ug/kg SEX/DURATION : female 1 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina REFERENCE : JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 30,55,1972 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE : 20 mg/kg SEX/DURATION : female 4 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility REFERENCE : BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 20,384,1979 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE : 3 gm/kg SEX/DURATION : male 6 day(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands REFERENCE : JOENAK Journal of Endocrinology. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1939- Volume(issue)/page/year: 51,241,1971 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - guinea pig DOSE : 150 mg/kg SEX/DURATION : female 28-58 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - delayed effects REFERENCE : HOBEAO Hormones and Behavior. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 6,139,1975 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Implant SPECIES OBSERVED : Mammal - cattle DOSE : 208 mg/kg SEX/DURATION : male 82 day(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - other effects on male REFERENCE : JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 94,57,1992 *** END OF RECORD ***