*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BV8154100
CHEMICAL NAME           : Androst-4-ene-3,11-dione, 17-beta-hydroxy-17-methyl-
CAS REGISTRY NUMBER     : 5419-48-7
BEILSTEIN REFERENCE NO. : 3158705
REFERENCE               : 4-08-00-02171 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H28-O3
MOLECULAR WEIGHT        : 316.48
WISWESSER LINE NOTATION : L E5 B666 CV OV MUTJ A1 E1 FQ F1
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * Androst-4-ene-3,11-dione, 17-hydroxy-17-methyl-, (17-beta)-
   * 17-beta-Hydroxy-17-methyl-4-androstene-3,11-dione
   * U-4407
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 800 mg/kg
SEX/DURATION            : female 3-10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
   Reproductive - Fertility - abortion
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 39,319,1974
 
                            *** END OF RECORD ***