*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BV8383000
CHEMICAL NAME           : Androst-4-en-3-one,
                          11-beta,17-beta-dihydroxy-17-methyl-
CAS REGISTRY NUMBER     : 1043-10-3
BEILSTEIN REFERENCE NO. : 3214017
REFERENCE               : 4-08-00-02056 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H30-O3
MOLECULAR WEIGHT        : 318.50
WISWESSER LINE NOTATION : L E5 B666 OV MUTJ A1 CQ E1 FQ F1
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * Androst-4-ene-3-one, 11,17-dihydroxy-17-methyl-, (11-beta,17-beta)-
   * BA 51-08943
   * 17-alpha-Methyl-11-beta,17-dihydroxy-4-androsten-3-one
   * U-5437
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 800 mg/kg
SEX/DURATION            : female 3-10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
   Reproductive - Fertility - abortion
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 39,319,1974
 
                            *** END OF RECORD ***