*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BX2610000
CHEMICAL NAME           : Aniline, 2,5-dichloro-
CAS REGISTRY NUMBER     : 95-82-9
BEILSTEIN REFERENCE NO. : 1447438
REFERENCE               : 4-12-00-01250 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 13
MOLECULAR FORMULA       : C6-H5-Cl2-N
MOLECULAR WEIGHT        : 162.02
WISWESSER LINE NOTATION : ZR BG EG
SYNONYMS/TRADE NAMES :
   * Amarthol Fast Scarlet GG Base
   * Amarthol Fast Scarlet GGS Base
   * Azobase DCA
   * Azoene Fast Scarlet 2G Base
   * Azogene Fast Scarlet GGC
   * Azogene Fast Scarlet GG (free base)
   * Azoic Diazo Component 3
   * Benzenamine, 2,5-dichloro-
   * C.I. 37010
   * C.I. Azoic Diazo Component 3
   * Daito Scarlet Base GG
   * Devol Scarlet A (free base)
   * Devol Scarlet 2GS Base
   * Diazo Fast Scarlet GG
   * 2,5-Dichloranilin
   * 2,5-Dichloroaniline
   * 2,5-Dichlorobenzenamine
   * Fast Red SGG Base
   * Fast Scarlet Base ggt
   * Fast Scarlet Base 2J
   * Fast Scarlet Base 2JS
   * Fast Scarlet DS Base
   * Fast Scarlet 2G
   * Fast Scarlet 2G Base
   * Fast Scarlet GG Base
   * Fast Scarlet GGS Base
   * Fast Scarlet MDC Base
   * Hiltonil Fast Scarlet 2G Base
   * Hiltonil Fast Scarlet 2GS Base
   * Hindamine Scarlet GG
   * Kambamine Scarlet GG base
   * Kayaku Scarlet GG Base
   * Lake Scarlet GG Base
   * Mitsui Scarlet GG base
   * Naphthanil Scarlet 2G Base
   * Naphtoelan Fast Scarlet GG Base
   * Sanyo Fast Scarlet GG Base
   * Scarlet Base Ciba I
   * Scarlet Base GG
   * Scarlet Base IRGA I (free base)
   * Scarlet Base NGG
   * Scarlet 2G Base
   * Spectrolene Scarlet 2G
   * Stabamine Scarlet GG
   * Symulon Scarlet 2G Base
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS 206512
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS 206512
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS 206512
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS 206512
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#00202
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 3750 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 33(4),8,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 3750 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 33(4),8,1968
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 27300 mg/kg/13W-I
TOXIC EFFECTS :
   Endocrine - changes in spleen weight
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - true cholinesterase
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - catalases
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 33(4),8,1968

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X4027
       No. of Facilities: 116 (estimated)
       No. of Industries: 3
       No. of Occupations: 6
       No. of Employees: 2820 (estimated)
       No. of Female Employees: 246 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   47,26992,82

   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***