*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : BX2610000 CHEMICAL NAME : Aniline, 2,5-dichloro- CAS REGISTRY NUMBER : 95-82-9 BEILSTEIN REFERENCE NO. : 1447438 REFERENCE : 4-12-00-01250 (Beilstein Handbook Reference) LAST UPDATED : 199710 DATA ITEMS CITED : 13 MOLECULAR FORMULA : C6-H5-Cl2-N MOLECULAR WEIGHT : 162.02 WISWESSER LINE NOTATION : ZR BG EG SYNONYMS/TRADE NAMES : * Amarthol Fast Scarlet GG Base * Amarthol Fast Scarlet GGS Base * Azobase DCA * Azoene Fast Scarlet 2G Base * Azogene Fast Scarlet GGC * Azogene Fast Scarlet GG (free base) * Azoic Diazo Component 3 * Benzenamine, 2,5-dichloro- * C.I. 37010 * C.I. Azoic Diazo Component 3 * Daito Scarlet Base GG * Devol Scarlet A (free base) * Devol Scarlet 2GS Base * Diazo Fast Scarlet GG * 2,5-Dichloranilin * 2,5-Dichloroaniline * 2,5-Dichlorobenzenamine * Fast Red SGG Base * Fast Scarlet Base ggt * Fast Scarlet Base 2J * Fast Scarlet Base 2JS * Fast Scarlet DS Base * Fast Scarlet 2G * Fast Scarlet 2G Base * Fast Scarlet GG Base * Fast Scarlet GGS Base * Fast Scarlet MDC Base * Hiltonil Fast Scarlet 2G Base * Hiltonil Fast Scarlet 2GS Base * Hindamine Scarlet GG * Kambamine Scarlet GG base * Kayaku Scarlet GG Base * Lake Scarlet GG Base * Mitsui Scarlet GG base * Naphthanil Scarlet 2G Base * Naphtoelan Fast Scarlet GG Base * Sanyo Fast Scarlet GG Base * Scarlet Base Ciba I * Scarlet Base GG * Scarlet Base IRGA I (free base) * Scarlet Base NGG * Scarlet 2G Base * Spectrolene Scarlet 2G * Stabamine Scarlet GG * Symulon Scarlet 2G Base *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1600 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1600 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 56 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00202 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 3750 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 33(4),8,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 3750 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 33(4),8,1968 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 27300 mg/kg/13W-I TOXIC EFFECTS : Endocrine - changes in spleen weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - catalases REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 33(4),8,1968 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4027 No. of Facilities: 116 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 2820 (estimated) No. of Female Employees: 246 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 47,26992,82 EPA TSCA Section 8(d) unpublished health/safety studies EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998 *** END OF RECORD ***